Nidoviruses

With the emergence of severe acute respiratory syndrome (SARS) and the increased interest in all nidoviruses, the urgent need for a comprehensive book on the subject has never been more evident. Nidoviruses is the first volume to cover the entire nidovirus order, including arteriviruses, toroviruses, roniviruses, and several recently identified human coronaviruses. Ranging from basic biology to immunology and clinical disease, this volume provides crucial information for researchers in virology, epidemiology, biochemistry, cell biology, pathogenesis, and antiviral drug development.

Organized into 26 highly accessible and well-illustrated chapters, Nidoviruses synthesizes the most recent research on the basic microbiology of nidoviruses, their genetic replication, and immune system responses. Widely respected experts address the impact of the recently developed systems for nidovirus reverse genetics, the unique mechanism of nidovirus RNA synthesis, virus-host cell interactions, emerging nidovirus infections, and potential targets for therapeutic interventions.


With this new knowledge, scientists and public health officials will be better positioned to recognize future nidovirus outbreaks and will be better able to take appropriate quarantine, vaccination, and therapeutic antiviral measures. This book will surely be used to save human and animal lives in the event of future epidemics and will be essential reading for specialists and for those interested in viral replication and pathogenesis.